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You are here: Home / Archives for HEALTH

Will prolong the pandemic: WHO chief Tedros Ghebreyesus warns against ‘COVID vaccine nationalism’

October 26, 2020 by Nasheman

Several dozen vaccine candidates are currently being tested in clinical trials, ten of which are in the most advanced ‘phase-III’ stage involving tens of thousands of volunteers.

WHO chief Tedros Adhanom Ghebreyesus

BERLIN: The head of the World Health Organization (WHO) on Sunday called for global solidarity in the rollout of any future coronavirus vaccine, as the number of cases soared across the world.

In a video address at the opening of the three-day World Health Summit in Berlin, Tedros Adhanom Ghebreyesus said the only way to recover from the pandemic was together and by making sure poorer countries had fair access to a vaccine.

“It is natural that countries want to protect their own citizens first but if and when we have an effective vaccine, we must also use it effectively. And the best way to do that is to vaccinate some people in all countries rather than all people in some countries. Let me be clear: vaccine nationalism will prolong the pandemic, not shorten it,” he said.

Scientists around the world are racing to develop a vaccine against COVID-19, which has killed over 1.1 million people. Several dozen vaccine candidates are currently being tested in clinical trials, ten of which are in the most advanced “phase 3” stage involving tens of thousands of volunteers.

The European Union, the United States, Britain, Japan and a slew of other nations have already placed large orders with the companies involved in developing the most promising vaccines. But concerns are growing that countries with smaller wallets could be left at the back of the queue.

The WHO has launched an international scheme known as Covax to help ensure equitable access to jabs, but it has struggled to raise the funds needed.

The WHO on Sunday reported a third straight day of record new infections across the world, calling on countries to take further action to curb the spread of the disease. The agency’s figures showed that 465,319 cases were declared for Saturday alone, half of them in Europe. “This is a dangerous moment for many countries in the northern hemisphere as cases spike,” Tedros said.

But he added that people weren’t powerless against the virus, stressing the importance of social distancing, hand washing, and meeting outdoors instead of inside. “Again and again we have seen that taking the right actions quickly means the outbreak can be managed,” he added.

Speaking at the same summit, which is being held online this year, United Nations Secretary-General Antonio Guterres in his video message called the pandemic “the greatest crisis of our times”.

“We need global solidarity every step of the way. A vaccine must be global public good Vaccines, tests and therapies are more than life savers. They are economy savers and society savers,” he said, echoing the plea for developed countries to support those with fewer resources.

Filed Under: HEALTH, World

With spike of 45,149 cases, India’s COVID-19 tally reaches 79,09,960

October 26, 2020 by Nasheman

The number of total active COVID-19 cases stood at 6,53,717 after a decrease of 14,437 in the last 24 hours. Total cured cases stand at 71,37,229 with 59,105 new discharges in the last 24 hours.

NEW DELHI: With 45,149 new COVID-19 cases, India’s total cases surged to 79,09,960 on Monday, according to the Ministry of Health and Family Welfare

With 480 new deaths, the COVID-19 toll mounted to 1,19,014, as per the Union Health Ministry.

The number of total active COVID-19 cases stood at 6,53,717 after a decrease of 14,437 in the last 24 hours. Total cured cases stand at 71,37,229 with 59,105 new discharges in the last 24 hours.

With 1,41,001 total active cases, Maharashtra continues to be the worst affected state by COVID-19 in the country. While 14,60,755 patients have recovered from the disease in the state, 43,264 have died so far.

Among other severely affected states, Karnataka has 81,069 active cases, while 7,10,843 people have recovered and 10,905 have succumbed to the coronavirus.

Kerala has 96,688 active cases, while 2,94,910 patients have been cured so far in the state along with 1,332 deaths reported due to the disease.

West Bengal has 37,017 active cases, while Tamil Nadu and the national capital Delhi have 30,606 and 26,744 active cases respectively.

Meanwhile, a total of 10,34,62,778 samples tested for COVID-19 up to 25th October. Of these 9,39,309 samples were tested yesterday, according to the Indian Council of Medical Research (ICMR). 

Filed Under: HEALTH, India

COVID-19 Update India 53,370 new cases take India’s tally to 78.14 lakh, death toll at 1,17,956

October 24, 2020 by Nasheman

There are 6,80,680 active cases of coronavirus infection in the country which comprises 8.71 per cent of the total caseload, the ministry data said.

India’s COVID-19 tally climbed to 78.14 lakh with 53,370 fresh cases in a day, while 70,16,046 people have so far recuperated pushing the national recovery rate to 89.78 per cent on Saturday, the Union health ministry said.

The total number of coronavirus cases mounted to 78,14,682 and the death toll to 1,17,956, with the novel coronavirus virus claiming  650 lives in a span of 24 hours in the country, the ministry data updated at 8 am on Saturday showed.

The COVID-19 case fatality rate has further declined to 1.51 per cent.

There are 6,80,680 active cases of coronavirus infection in the country which comprises 8.71 per cent of the total caseload, the ministry data said.

Filed Under: HEALTH, India

Oxford COVID-19 vaccine doing ‘everything expected’, independent study finds

October 23, 2020 by Nasheman

Once inside a human cell the genetic instructions for the spike protein need to be ‘photocopied’ many times — a process known as “transcription”.

LONDON: The Oxford University COVID-19 vaccine undergoing Phase III clinical trials with British pharma giant AstraZeneca is doing “everything expected” which means good news in the fight against the deadly virus, an independent analysis said on Thursday.

A team at Bristol University used recently developed techniques to validate that the vaccine accurately follows the genetic instructions programmed into it by the Oxford University team.

The experts say that the novel analysis provides even greater clarity and detail about how the vaccine successfully provokes a strong immune response.

“This is an important study as we are able to confirm that the genetic instructions underpinning this vaccine, which is being developed as fast as safely possible, are correctly followed when they get into a human cell,” said Dr David Matthews, Reader in Virology from Bristol’s School of Cellular and Molecular Medicine (CMM), who led the research.

“Until now, the technology hasn’t been able to provide answers with such clarity, but we now know the vaccine is doing everything we expected and that is only good news in our fight against the illness,” he said.

The vaccine, ChAdOx1 nCoV-19 and also known as AZD1222, is considered among the most advanced in the worldwide hunt for a viable vaccine against the novel coronavirus.

The findings, published on the pre-print server “ResearchSquare’, represent the most in-depth analysis of any of the COVID-19 vaccine candidates, going significantly above and beyond” any regulatory requirements anywhere in the world.

“This is a wonderful example of cross-disciplinary collaboration, using new technology to examine exactly what the vaccine does when it gets inside a human cell,” said Sarah Gilbert, Professor of Vaccinology at the University of Oxford and lead on the Oxford vaccine trial.

“The study confirms that large amounts of the coronavirus spike protein are produced with great accuracy, and this goes a long way to explaining the success of the vaccine in inducing a strong immune response,” she said.

Work on the vaccine, developed by researchers at the University of Oxford’s Jenner Institute and Oxford Vaccine Group, began in January this year.

Now undergoing Phase III clinical trials by the University of Oxford and biopharma giant AstraZeneca, the Bristol researchers’ focus was to assess how often and how accurately the vaccine is copying and using the genetic instructions provided by the Oxford team.

These instructions detail how to make the spike protein from the coronavirus, SARS-CoV-2 that causes COVID-19. The Oxford vaccine is made by taking a common cold virus (adenovirus) from chimpanzees and deleting about 20 per cent of the virus’s instructions.

This means it is impossible for the vaccine to replicate or cause disease in humans, but it can still be produced in the laboratory under special conditions. By removing these genetic instructions there is space to add the instructions for the spike protein from SARS-CoV-2.

Once inside a human cell the genetic instructions for the spike protein need to be ‘photocopied’ many times — a process known as “transcription”.

In any vaccine system, it is these so-called photocopies that are directly used to make large amounts of the spike protein. Once the spike protein is made, the immune system will react to it and this pre-trains the immune system to identify a real COVID-19 infection. So, when the person vaccinated is confronted with the SARS-CoV-2 virus their immune system is pre-trained and ready to attack it.

Oxford University said that adenoviruses have been used for many years to make vaccines, and these are always tested to very high standards to make sure every batch of vaccine has the correct copy of genetic instructions embedded in the vaccine.

“However, thanks to very recent advances in genetic sequencing and protein analysis technology, researchers at Bristol were for the first time also able to directly check thousands and thousands of the ‘photocopied’ instructions produced by the Oxford vaccine within a cell. In this way they were able to directly validate that the instructions are copied correctly and accurately, providing greater assurance that the vaccine is performing exactly as programmed,” the university explained.

At the same time, the researchers checked the spike protein being made by the vaccine inside human cells also accurately reflects the instructions as programmed. This brand-new approach may be more routinely used in the future to help researchers finetune the performance of these kinds of vaccines.

The study was funded by the Biotechnology and Biological Sciences Research Council (BBSRC), the United States Food and Drug Administration (US FDA) and the Engineering and Physical Sciences Research Council (EPSRC).

Filed Under: HEALTH, World

COVID-19 Updates: India records 54,366 new infections, 690 deaths as tally crosses 77.6 lakh mark

October 23, 2020 by Nasheman

A total of 54,366 new infections were reported in a day, while the death toll climbed to 1,17,306 with 690 fatalities, the data updated at 8 am showed.

COVID-19 recoveries in India have crossed 69 lakh, while the number of coronavirus infections reported in a span of 24 hours remained below 60,000 for the fifth consecutive day as the country’s caseload rose to 77,61,312, according to Union Health Ministry data updated on Friday

A total of 54,366 new infections were reported in a day, while the death toll climbed to 1,17,306 with 690 fatalities, the data updated at 8 am showed.

The number of active cases of the coronavirus infection is below 7 lakh.

There are 6,95,509 active cases of COVID-19 in the country as on date which comprises 8.96 per cent of the total caseload, the data stated.

A total of 69,48,497 people have recuperated from the disease so far pushing the national recovery rate to 89.53 per cent while the case fatality rate due to COVID-19 was recorded at 1.51 per cent.

India’s COVID-19 tally had crossed the 20-lakh mark on August 7, 30 lakh on August 23 and 40 lakh on September 5.

It went past 50 lakh on September 16, 60 lakh on September 28 and crossed 70 lakh on October 11.

According to the Indian Council of Medical Research (ICMR), a cumulative total of 10,01,13,085 samples have been tested up to October 22 with 14,42,722 samples being tested on Thursday.

The 690 new fatalities include 198 from Maharashtra, 74 from Karnataka, 64 from West Bengal, 52 from Chhattisgarh, 45 from Tamil Nadu and 35 each from Uttar Pradesh and Delhi.

The total 1,17,306 deaths reported so far in the country include 42,831 from Maharashtra, 10,825 from Tamil Nadu, 10,770 from Karnataka, 6,790 from Uttar Pradesh, 6,524 from Andhra Pradesh, 6,308 from West Bengal, 6,163 from Delhi, 4,072 from Punjab and 3,667 from Gujarat.

The health ministry stressed that more than 70 per cent of the deaths occurred due to comorbidities.

“Our figures are being reconciled with the Indian Council of Medical Research,” the ministry said on its website and added that state-wise distribution of figures is subject to further verification and reconciliation.

Filed Under: HEALTH, India

Maharashtra COVID numbers at 16,17,658 with 8,142 new cases; 23,371 discharged

October 22, 2020 by Nasheman

Mumbai city reported 1,609 positive cases during the day, which pushed its overall case count to 2,45,869, while its death toll rose to 9,912, of which 48 were reported today.

MUMBAI: Maharashtra’s COVID-19 tally on Wednesday increased to 16,17,658 with the single-day rise of 8,142 cases, a state health official said.

The state also reported 180 deaths, which took the fatality count to 42,633, he said.

A total of 23,371 patients were discharged during the day after treatment, taking the tally of recovered people to 14,15,679.

With this, the number of active patients in the state stands at 1,58,852.

Mumbai city reported 1,609 positive cases during the day, which pushed its overall case count to 2,45,869, while its death toll rose to 9,912, of which 48 were reported today.

Pune city added 442 COVID-19 cases, raising its tally to 1,69,178, while three deaths took toll to 3,876. The state has so far conducted 83,27,493 tests.

Maharashtra’s COVID-19 tally is as follows: Positive cases: 16,17,658, new cases: 8,142, death toll: 42,633, discharged: 14,15,679, active cases: 1,58,852, people tested so far: 83,27,493.

Filed Under: HEALTH, India

COVID-19 Updates IN india Virus infection cases in India cross 77 lakh-mark, death toll at 1,16,616

October 22, 2020 by Nasheman

Total case tally in the country stands at 77,06,946 including 7,15,812 active cases and 68,74,518 recovered.

India on Thursday recorded 55,838 fresh cases of virus infection and 702 deaths. 

Total case tally in the country stands at 77,06,946 including 7,15,812 active cases, 68,74,518 recovered and 1,16,616 deaths, according to the Ministry of Health and Family Welfare.

As the country proceeds towards the winter season, experts said that cooler weather is likely to worsen as it happens with most viruses that attack the respiratory tract and may lead to possibly a second, even a bigger wave of cases and deaths in the country.

Filed Under: HEALTH, India

New COVID-19 cases remain below 60,000 mark for the third consecutive day, India tally nears 77,000

October 21, 2020 by Nasheman

A total of 54,044 fresh infections were reported in a day, while the death toll climbed to 1,15,914 with 717 fatalities being registered in a span of 24 hours, the data updated at 8 am showed

NEW DELHI: The number of new coronavirus infections reported in India in a span of 24 hours remained below 60,000 for the third consecutive day, taking the COVID-19 caseload to 76,51,107, according to the Union Health Ministry data updated on Wednesday.

A total of 54,044 fresh infections were reported in a day, while the death toll climbed to 1,15,914  with 717 fatalities being registered in a span of 24 hours ,the data updated at 8 am showed.

As many as 67,95,103 people have recuperated from the disease so far pushing the national recovery rate to 88.81 per cent while the case fatality rate due COVID-19 has dropped to 1.51 per cent.

The active cases of coronavirus infection remained below 8 lakh for the fifth consecutive day.

There are 7,40,090 active cases of coronavirus infection in the country which comprises 9.67 per cent of the total caseload, the data stated.

India’s COVID-19 tally had crossed the 20-lakh mark on August 7, 30 lakh on August 23 and 40 lakh on September 5.

It went past 50 lakh on September 16,  60 lakh on September 28 and crossed 70 lakh on October 11.

According to the ICMR, a cumulative total of 9,72,00,379 samples have been tested up to October 20 with 10,83,608 samples being tested on Tuesday.

The 717 new fatalities include 213 from Maharashtra, 66 from Karnataka, 61 from West Bengal, 50 each from Chhattisgarh and Tamil Nadu, and 41 from Delhi.

A total of 1,15,914 deaths have been reported so far in the country including 42,453 from Maharashtra followed by 10,741 from Tamil Nadu, 10,608 from Karnataka, 6,714 from Uttar Pradesh, 6,481 from Andhra Pradesh, 6,180 from West Bengal, 6,081 from Delhi, 4,037 from Punjab and 3,651 from Gujarat.

The health ministry stressed that more than 70 per cent of the deaths occurred due to comorbidities.

“Our figures are being reconciled with the Indian Council of Medical Research,” the ministry said on its  website, adding that state-wise distribution of figures is subject to further verification and reconciliation.

Filed Under: HEALTH, India

Air Pollution is the highest health risk for newborns in India: Study

October 21, 2020 by Nasheman

More than half of these deaths were associated with outdoor  PM 2.5 and others were linked to use of solid fuels such as charcoal, wood, and animal dung for cooking.  

Delhi Pollution

NEW DELHI: A comprehensive analysis  of  air  pollution’s  global  impact  on  newborns  finds  that outdoor  and household  particulate  matter  pollution  contributed  to the  deaths  of  more than 116,000 Indian infants in  their  first month of  life  in 2019,  according  to a  new  global  study, State of Global Air 2020 (SoGA).  

More than half of these deaths were associated with outdoor  PM 2.5 and others were linked to use of solid fuels such as charcoal, wood, and animal dung for cooking.

Long-term  exposure  to outdoor  and  household  air  pollution  contributed to  over  1.67 million annual  deaths from  stroke, heart  attack, diabetes, lung  cancer, chronic  lung  diseases, and  neonatal diseases, in India  in 2019.  

For  the  youngest infants, most deaths were related to complications from low birth weight  and preterm birth.  

The  report  highlights  the  ongoing  challenge  of  high outdoor  air  pollution — South Asian countries including India, Bangladesh, Pakistan  and Nepal  feature  among  the  top  ten  countries  with the highest  PM 2.5  exposures  in 2019;  all of these  countries  experienced increases  in  outdoor  PM2.5 levels  between  2010 and  2019. 

Use  of  solid fuels  for  cooking, however,  presents  a  pattern of  moderate  success. Since  2010, more than 50  million fewer people  have  been exposed  to household  air  pollution. The  Pradhan  Mantri Ujjwala  Yojana Household  LPG program  and  other  schemes  have helped  to  dramatically  expand access  to  clean  energy,  especially  for  rural households.

 This report  comes  as  COVID-19 — a disease for  which  people with  heart  and  lung  disease are particularly at  risk of  infection and  death — has  claimed  more than  110,000  lives  in India. 

Although the  full  links  between air  pollution  and  COVID-19  are  not  yet  known, there  is  clear evidence  linking  air  pollution  and  increased  heart and  lung  disease  creating  a  growing  concern that  exposures  to high  levels  of  air  pollution, during  winter  months in South Asian countries  and East  Asia, could  exacerbate the effects of  COVID-19. 

“An  infant’s  health  is  critical  to  the future of  every  society,  and  this newest  evidence suggests  an  especially high  risk for  infants  born  in  South Asia  and sub-Saharan  Africa,” said  Dan  Greenbaum,  President  of  HEI. 

“Although  there  has  been slow  and steady reduction  in  household  reliance  on poor-quality fuels, the  air pollution from  these  fuels  continues  to be  a  key factor  in the  deaths  of  these  youngest  infants,” he added. 

Infants  in  the  first  month  of  life  are  already  at  a  vulnerable  stage. But  a  growing  body of scientific  evidence from  multiple  countries,  including  recent ICMR-supported  studies  in  India, indicates that  particulate  air pollution exposure  during  pregnancy is  linked  to low  birth weight  and pre-term  birth.

These  latter  conditions, both of  which are  associated with  serious  complications, already account for the vast majority of  deaths in the neonatal period  (455,000  in  2019).  

The  new  analysis  reported  in the  State  of  Global Air  this  year  estimates  that nearly  21 per cent of neonatal deaths from  all  causes  are  attributable  to ambient and household air  pollution. 

“Addressing impacts  of  air  pollution on  adverse  pregnancy outcomes  and newborn  health  is  really important  for low- and middle-income  countries, not  only because of the high prevalence  of low  birth weight, preterm  birth, and child  growth deficits but  because  it allows the design of strategic  interventions  that  can be  directed  at  these vulnerable  groups,”  said  Dr.  Kalpana Balakrishnan,  an  air pollution and health expert who was not involved with the study.   

The  State  of  Global  Air  2020  annual  report  and accompanying  interactive  website  are  designed and implemented  by the  Health  Effects  Institute  in cooperation with  the Institute for Health Metrics and Evaluation (IHME2) at  the  University of  Washington,  and  the  University  of  British Columbia; its findings  are  based  on the most  recent  Global  Burden  of  Disease (GBD3)  Study  published  in the  international medical  journal, The  Lancet on October  15, 2020.

Filed Under: HEALTH, India

India COVID-19 daily caseload drops below 50,000 mark three months after, death toll crosses 1.15 lakh

October 20, 2020 by Nasheman

A total of 46,790 fresh infections were reported in a day, while the death toll climbed to 1,15,197 with 587 fatalities being registered in a span of 24 hours, the data updated at 8 am showed

NEW DELHI: The number of new coronavirus infections reported daily in India dropped below 50,000 for the first time in nearly three months, taking the COVID-19 caseload to 75,97,063 on Tuesday, according to the Union Health Ministry.

A total of 46,790 fresh infections were reported in a day, while the death toll climbed to 1,15,197 with 587 fatalities being registered in a span of 24 hours, the data updated at 8 am showed.

The number of new fatalities reported daily across the country was recorded below 600 for the second consecutive day.

The total recoveries crossed 67 lakh while active cases of coronavirus infection remained below 8 lakh for the fourth consecutive day.

The country had reported 47,703 new infections in a day on July 28.

There are 7,48,538 active cases of coronavirus infection in the country which comprises 9.85 per cent of the total caseload, the data stated.

A total 67,33,328 people have recuperated from the disease so far pushing the national recovery rate to 88.63 per cent while the case fatality rate due COVID-19 stands at 1.52 per cent.

India’s COVID-19 tally had crossed the 20-lakh mark on August 7, 30 lakh on August 23 and 40 lakh on September.

It went past  50 lakh on September 16, 60 lakh on September 28 and crossed 70 lakh on October 11.

According to the ICMR, a cumulative total of 9,61,16,771 samples have been tested up to October 19 with 10,32,795 samples being tested on Monday.

The 579 new fatalities include 125 from Maharashtra, 64 from Karnataka, 63 from West Bengal, 56 from  Chhattisgarh, 49 from Tamil Nadu, and 31 from Delhi.

A total of 1,15,197 deaths have been reported so far in the country including 42,240 from Maharashtra followed by 10,691 from Tamil Nadu, 10,542 from Karnataka, 6,685 from Uttar Pradesh, 6,453 from Andhra Pradesh, 6,119 from West Bengal, 6,040 from Delhi, 4,029 from Punjab and 3,643 from Gujarat.

The health ministry stressed that more than 70 per cent of the deaths occurred due to comorbidities.

“Our figures are being reconciled with the Indian Council of Medical Research,” the ministry said on its  website, adding that state-wise distribution of figures is subject to further verification and reconciliation.

Filed Under: HEALTH, India

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