The state-wide shutdown is backed by opposition parties including the Rashtriya Janata Dal (RJD) (RJD), Congress, Hindustani Swam Morcha, Samajwadi Party and Lokrantrik Janata Dal.
Left party workers and supporters blocked railway tracks thereby affecting over a dozen trains since early Thursday morning.
According to reports reaching here, trains were stopped in Darbhanga, Madhubani, Jahanabad, Gaya, Muzaffarpur, Patna and Bhojpur districts.
Protesters have also blocked several roads in Siwan, Bhojpur, Nawada, Patna, Arwal, Jagabad districts.
The case came to light earlier this year when the Bihar Social Welfare Department filed an FIR based on a social audit of the shelter home conducted by the Tata Institute of Social Sciences (TISS), Mumbai.
The CBI on Sunday took over case following a recommendation by Bihar Chief Minister Nitish Kumar.